In vitro reports have revealed that sildenafil is selective for phosphodiesterase-5 (PDE5) . Its result is more powerful on PDE5 than on other known phosphodiesterases . Specifically, there is a 10-instances selectivity more than PDE6 which happens to be involved in the phototransduction pathway within the retina .

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The observed rise in sildenafil bioavailability is not likely for being of medical importance for most folks.

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This medication isn't going to safeguard you towards sexually transmitted illnesses (including HIV or AIDS). Use protecting steps and question your medical professional For those who have any questions about this.